Structures of Omicron spike complexes and implications for neutralizing antibody development
Summary: The emergence of the SARS-CoV-2 Omicron variant is dominant in many countries worldwide.The high number of spike mutations is responsible depileve easy clean for the broad immune evasion from existing vaccines and antibody drugs.To understand this, we first present the cryo-electron microscopy structure of ACE2-bound SARS-CoV-2 Omicron spi